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I also benchmarked my changes from yesterday (swapping out the Fastq read function). It seems saligner is now faster than readaligner (at least in exact matching). Anyways, here are the times:
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The mismatch:exact ratio is still a bit off from bowtie's and readaligner's, but that might also be because mismatches still unecessarily go through the CIGAR generator (which I should fix sometime). |