Vancouver, British Columbia
[at] mrl [dot] ubc [dot] ca
phone: (604) 682-2344 ext. 62868
I am currently a postdoctoral fellow at the James Hogg iCAPTURE Centre in St Paul's Hospital under the supervision of Dr. Keith Walley and Dr. Mark Wilkinson. My research interests include bioinformatics, computational biology and clinical genomics. Currently, I’m working on indentifying the genetic variants that predispose an individual to susceptibility for inflammatory diseases and predict responses to therapy. My research consists on developing a high throughput Whole Genome Association methodology that efficiently identifies, in an unbiased way, many genetic variants that influence important clinical outcomes of inflammatory diseases.
For my PhD thesis I improved the performance and scope of algorithmic methods for the design of RNA strands that are predicted to fold to a given secondary structure, according to a standard thermodynamic model. The design of RNA structures is important for applications in therapeutics and nanotechnology. My research consisted on investigating the empirical complexity of this problem, on designing stable structures according to several parameters, and on designing complexes of RNA molecules, that is, RNA molecules that interact with each other. My PhD supervisors were Anne Condon and Holger Hoos. In April 2007, I defended my Ph.D. thesis " Computational RNA Secondary Structure Design: Empirical Complexity and Improved Methods".