| Abstract |
The Pearson's chi-squared test is a popular statistical method used in biological experiments to determine the independance of two events. I will discuss how it is applied to the case-control data in the paper Mapping Trait Loci by Use of Inferred Ancestral Recombination Graphs to determine statistical associations between a loci and the disease. And try to answer the question of why applying a chi-squared test on Ancestral Recombination Graphs would produce more accurate results than applying the chi-squared tests on just the case-control data.
Notes written by Paul Lu
|