| Title: | How microRNAs choose their targets, Ivo Hofacker, Nature Genetics 39, 1191 - 1192 (2007) |
| Speaker: |
Mirela Andronescu
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| Abstract |
The growing list of known microRNAs is only as useful as our ability to identify the mRNA targets they control. A new study stresses the role of messenger RNA structure in microRNA target recognition and suggests that binding of the RNA-induced silencing complex is largely controlled by the thermodynamics of RNA-RNA interactions.
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